Nier Replicant v1.22 followed by a hord of nonsensical figures is a remastered edition of the original Nier Replicant game from 2010. I actually remember it because I had it on Xbox 360 at the time. The Remaster was just released on the 23rd of April 2021, and the good news is that it works out of the box on Proton on most configurations, as indicated by a Gold rating on ProtonDB. Here’s the game as streamed by a Linux user on Nvidia:

Funny fact is that Nier Automata was the one game that pushed Philip Rebhole, the lead developer behind DXVK, to implement DX11 on top of Vulkan. Now, many years later, seeing the prequel to Automata working very nicely at release vindicates all these efforts once again.